Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems

BACKGROUND: Cytolytic cells of the immune system destroy pathogen-infected cells by polarised exocytosis of secretory lysosomes containing the pore-forming protein perforin. Precise delivery of this lethal hit is essential to ensuring that only the target cell is destroyed. In cytotoxic T lymphocyte...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Stinchcombe, Jane C, Salio, Mariolina, Cerundolo, Vincenzo, Pende, Daniela, Arico, Maurizo, Griffiths, Gillian M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149597/
https://ncbi.nlm.nih.gov/pubmed/21711522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-45
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares