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Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems
BACKGROUND: Cytolytic cells of the immune system destroy pathogen-infected cells by polarised exocytosis of secretory lysosomes containing the pore-forming protein perforin. Precise delivery of this lethal hit is essential to ensuring that only the target cell is destroyed. In cytotoxic T lymphocyte...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149597/ https://ncbi.nlm.nih.gov/pubmed/21711522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-45 |
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