walK and clpP Mutations Confer Reduced Vancomycin Susceptibility in Staphylococcus aureus

Vancomycin-intermediate Staphylococcus aureus (VISA) is generated from vancomycin-susceptible Staphylococcus aureus by multiple spontaneous mutations. We previously reported that sequential acquisition of mutations in the two-component regulatory systems vraSR and graRS was responsible for the VISA...

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Bibliographic Details
Main Authors: Shoji, Mitsutaka, Cui, Longzhu, Iizuka, Risa, Komoto, Akira, Neoh, Hui-min, Watanabe, Yukiko, Hishinuma, Tomomi, Hiramatsu, Keiichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147622/
https://ncbi.nlm.nih.gov/pubmed/21628539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01563-10
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