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Cloning, expression, purification, crystallization and preliminary crystallographic analysis of MsDpo4: a Y-family DNA polymerase from Mycobacterium smegmatis

The expression of error-prone DNA polymerases belonging to the Y-family is upregulated in prokaryotes under adverse conditions to facilitate adaptive mutagenesis. However, it has been suggested that representatives of this family in mycobacteria do not participate in adaptive mutagenesis. These stud...

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Detalhes bibliográficos
Main Authors: Sharma, Amit, Nair, Deepak T.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144803/
https://ncbi.nlm.nih.gov/pubmed/21795801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111019063
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