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Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy

Gastrointestinal dysfunction is common in diabetic patients. In genetic (nonobese diabetic) and toxin-elicited (streptozotocin) models of diabetes in mice, we demonstrate defects in gastric emptying and nonadrenergic, noncholinergic relaxation of pyloric muscle, which resemble defects in mice harbor...

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Main Authors: Watkins, Crystal C., Sawa, Akira, Jaffrey, Samie, Blackshaw, Seth, Barrow, Roxanne K., Snyder, Solomon H., Ferris, Christopher D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC314323/
https://ncbi.nlm.nih.gov/pubmed/10930440
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