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Amelioration of Lupus Nephritis by Serum Amyloid P Component Gene Therapy with Distinct Mechanisms Varied from Different Stage of the Disease

BACKGROUND: Our previous study revealed that administration of syngeneic female BALB/c mice with excessive self activated lymphocyte-derived DNA (ALD-DNA) could induce systemic lupus erythematosus (SLE) disease, indicating that overload of self-DNA might exceed normal clearance ability and comprise...

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Detalhes bibliográficos
Main Authors: Zhang, Weijuan, Wu, Jin, Qiao, Bin, Xu, Wei, Xiong, Sidong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143173/
https://ncbi.nlm.nih.gov/pubmed/21799927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022659
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