Molecular alterations associated with liver metastases development in colorectal cancer patients

BACKGROUND: Understanding the molecular biology of colorectal cancer (CRC) provides opportunities for effective personalised patient management. We evaluated whether chromosomal aberrations, mutations in the PI(3)K signalling pathway and the CpG-island methylator phenotype (CIMP) in primary colorect...

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Main Authors: Bruin, S C, He, Y, Mikolajewska-Hanclich, I, Liefers, G-J, Klijn, C, Vincent, A, Verwaal, V J, de Groot, K A, Morreau, H, van Velthuysen, M-L F, Tollenaar, R A E M, van ‘t Veer, L J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142796/
https://ncbi.nlm.nih.gov/pubmed/21673680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.184
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