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A three-dimensional perspective on exon binding by a group II self-splicing intron
We have used chemical footprinting, kinetic dissection of reactions and comparative sequence analysis to show that in self-splicing introns belonging to subgroup IIB, the sites that bind the 5′ and 3′ exons are connected to one another by tertiary interactions. This unanticipated arrangement, which...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314214/ https://ncbi.nlm.nih.gov/pubmed/10990464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.18.5007 |
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