Interferon-γ inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T cell apoptosis

Interferon-gamma (IFN-γ) mediates responses to bacterial infection and autoimmune disease but it is also an important tumor suppressor. IFN-γ is upregulated in the gastric mucosa by chronic Helicobacter infection; however, whether it plays a positive or negative role in inflammation-associated gastr...

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Bibliografiske detaljer
Main Authors: Tu, Shui Ping, Quante, Michael, Bhagat, Govind, Takaishi, Shigeo, Cui, Guanglin, Yang, Xiang Dong, Muthuplani, Sureshkumar, Shibata, Wataru, Fox, James G., Pritchard, D. Mark, Wang, Timothy C.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139967/
https://ncbi.nlm.nih.gov/pubmed/21512143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4009
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