Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggers

Migraine is a common neurological disorder often treated with triptans. Triptan overuse can lead to increased frequency of headache in some patients, a phenomenon termed medication overuse headache. Previous preclinical studies have demonstrated that repeated or sustained triptan administration for...

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Autores principales: De Felice, Milena, Ossipov, Michael H., Wang, Ruizhong, Dussor, Gregory, Lai, Josephine, Meng, Ian D., Chichorro, Juliana, Andrews, John S., Rakhit, Suman, Maddaford, Shawn, Dodick, David, Porreca, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139937/
https://ncbi.nlm.nih.gov/pubmed/20627971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq159
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