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Interleukin-10 Promoter Polymorphisms Influence HIV-1 Susceptibility and Primary HIV-1 Pathogenesis
IL-10 directly inhibits HIV-1 replication but it may also promote viral persistence by inactivation of effector immune mechanisms. Here we show in an African cohort that individuals with genotypes associated with high IL-10 production at two promoter single nucleotide polymorphisms (-1082 and -592)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137931/ https://ncbi.nlm.nih.gov/pubmed/19534595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600072 |
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