IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease

The kidney contains receptors for the cytokine IL-25, but the effects of IL-25 in CKD are unknown. Here, we induced adriamycin nephropathy in both BALB/c mice and severe combined immunodeficient (SCID) mice, and we injected IL-25 for 7 consecutive days starting at day 5 after adriamycin administrati...

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Bibliographic Details
Main Authors: Cao, Qi, Wang, Changqi, Zheng, Dong, Wang, Ya, Lee, Vincent W. S., Wang, Yuan Min, Zheng, Guoping, Tan, Thian Kui, Yu, Di, Alexander, Stephen I., Harris, David C. H., Wang, Yiping
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2011
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137571/
https://ncbi.nlm.nih.gov/pubmed/21719780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070693
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