A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility

Gene-gene interactions are proposed as one important component of the genetic architecture of complex diseases, and are just beginning to be evaluated in the context of genome wide association studies (GWAS). In addition to detecting epistasis, a benefit to interaction analysis is that it also incre...

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書誌詳細
主要な著者: Bush, William S., McCauley, Jacob L., DeJager, Philip L., Dudek, Scott M., Hafler, David A., Gibson, Rachel A., Matthews, Paul M., Kappos, Ludwig, Naegelin, Yvonne, Polman, Chris H., Hauser, Stephen L., Oksenberg, Jorge, Haines, Jonathan L., Ritchie, Marylyn D.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136581/
https://ncbi.nlm.nih.gov/pubmed/21346779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.3
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