A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility

Gene-gene interactions are proposed as one important component of the genetic architecture of complex diseases, and are just beginning to be evaluated in the context of genome wide association studies (GWAS). In addition to detecting epistasis, a benefit to interaction analysis is that it also incre...

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Detaylı Bibliyografya
Asıl Yazarlar: Bush, William S., McCauley, Jacob L., DeJager, Philip L., Dudek, Scott M., Hafler, David A., Gibson, Rachel A., Matthews, Paul M., Kappos, Ludwig, Naegelin, Yvonne, Polman, Chris H., Hauser, Stephen L., Oksenberg, Jorge, Haines, Jonathan L., Ritchie, Marylyn D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136581/
https://ncbi.nlm.nih.gov/pubmed/21346779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.3
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