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Na(+),K(+)-pump stimulation improves contractility in isolated muscles of mice with hyperkalemic periodic paralysis

In patients with hyperkalemic periodic paralysis (HyperKPP), attacks of muscle weakness or paralysis are triggered by K(+) ingestion or rest after exercise. Force can be restored by muscle work or treatment with β(2)-adrenoceptor agonists. A missense substitution corresponding to a mutation in the s...

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Bibliografske podrobnosti
Main Authors: Clausen, Torben, Nielsen, Ole Bækgaard, Clausen, Johannes D., Pedersen, Thomas Holm, Hayward, Lawrence J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135321/
https://ncbi.nlm.nih.gov/pubmed/21708955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010586
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