Acid-Sensitive Magnetic Nanoparticles as Potential Drug Depots

Superparamagnetic magnetic nanoparticles were successfully functionalized with poly(methacrylic acid) via atom transfer radical polymerization, followed by conjugation to doxorubicin (Dox). Because of pH-sensitive hydrazone linkages, the rate and extent of Dox release from the particles was higher a...

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Bibliographic Details
Main Authors: Wuang, Shy Chyi, Neoh, Koon Gee, Kang, En-Tang, Leckband, Deborah E., Pack, Daniel W.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134249/
https://ncbi.nlm.nih.gov/pubmed/21760639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/aic.12373
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