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Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor
Chromatin regulation is crucial for many biological processes such as transcriptional regulation, DNA replication, and DNA damage repair. We have found it is also important for neural stem/progenitor cell (NSC) function and neurogenesis. Here, we demonstrate that expression of the cyclin-dependent k...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130620/ https://ncbi.nlm.nih.gov/pubmed/21621175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2011.04.002 |
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