Phase I Study of Arsenic Trioxide, High-Dose Cytarabine and Idarubicin to Down-Regulate Constitutive STAT3 Activity in <60 Year Old Acute Myeloid Leukemia Patients

PURPOSE: Constitutive activation of signal transducer and activator of transcription-3 (STAT3) was detected in blasts from approximately 50% of acute myeloid leukemia (AML) patients and was found to correlate with adverse outcome. In vitro treatment of AML blasts with arsenic trioxide (ATO) down-reg...

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מידע ביבליוגרפי
Main Authors: Wetzler, Meir, Andrews, Chris, Ford, Laurie A., Tighe, Sheila, Barcos, Maurice, Sait, Sheila NJ, Block, AnneMarie W., Nowak, Norma J, Baer, Maria R., Wang, Eunice S, Baumann, Heinz
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129468/
https://ncbi.nlm.nih.gov/pubmed/21456022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26097
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