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RELATIONSHIP BETWEEN GENETIC VARIATION IN THE GLUTAMINASE GENE GLS1 AND BRAIN GLUTAMINE/GLUTAMATE RATIO MEASURED IN VIVO

BACKGROUND: Abnormalities in glutamatergic neurotransmission are implicated in several psychiatric disorders, but in vivo neurochemical studies of the glutamate system have been hampered by a lack of adequate probes. On the other hand, glutamine and glutamate can be quantified separately in proton m...

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Bibliographic Details
Main Authors: Öngür, Dost, Haddad, Stephen, Prescot, Andrew P., Jensen, J. Eric, Siburian, Richie, Cohen, Bruce M., Renshaw, Perry F., Smoller, Jordan W.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125415/
https://ncbi.nlm.nih.gov/pubmed/21457947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.01.033
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