Value of large scale expansion of tumor infiltrating lymphocytes in a compartmentalised gas-permeable bag: interests for adoptive immunotherapy

BACKGROUND: Adoptive cell therapy (ACT) has emerged as an effective treatment for patients with metastatic melanoma. However, there are several logistical and safety concerns associated with large-scale ex vivo expansion of tumour-specific T lymphocytes for widespread availability of ACT for cancer...

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Main Authors: Zuliani, Thomas, David, Julien, Bercegeay, Sylvain, Pandolfino, Marie-Christine, Rodde-Astier, Isabelle, Khammari, Amir, Coissac, Cécile, Delorme, Bruno, Saïagh, Soraya, Dréno, Brigitte
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125220/
https://ncbi.nlm.nih.gov/pubmed/21575188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-63
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