The Blood of Healthy Individuals Exhibits CD8 T Cells with a Highly Altered TCR Vb Repertoire but with an Unmodified Phenotype

CD8 T cell clonal expansions (TCE) have been observed in elderly, healthy individuals as well in old mice, and have been associated with the ageing process. Both chronic latent and non-persistent viral infections have been proposed to drive the development of distinct non-functional and functional T...

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Bibliographic Details
Main Authors: Degauque, Nicolas, Boeffard, Françoise, Foucher, Yohann, Ballet, Caroline, Brouard, Sophie, Soulillou, Jean-Paul
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124488/
https://ncbi.nlm.nih.gov/pubmed/21738624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021240
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