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Enhanced oral bioavailability of cyclosporine A by liposomes containing a bile salt

The main purpose of this study was to evaluate liposomes containing a bile salt, sodium deoxycholate (SDC), as oral drug delivery systems to enhance the oral bioavailability of the poorly water-soluble and poorly permeable drug, cyclosporine A (CyA). Liposomes composed of soybean phosphatidylcholine...

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Библиографические подробности
Главные авторы: Guan, Peipei, Lu, Yi, Qi, Jianping, Niu, Mengmeng, Lian, Ruyue, Hu, Fuqiang, Wu, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124400/
https://ncbi.nlm.nih.gov/pubmed/21720508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S19259
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