The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus Is the Determinant of Genome Attachment

The RNA-dependent RNA polymerase VP1 of infectious pancreatic necrosis virus (IPNV) is a single polypeptide responsible for both viral RNA transcription and genome replication. Sequence analysis identifies IPNV VP1 as having an unusual active site topology. We have purified, crystallized and solved...

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Main Authors: Graham, Stephen C., Sarin, L. Peter, Bahar, Mohammad W., Myers, Reg A., Stuart, David I., Bamford, Dennis H., Grimes, Jonathan M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121795/
https://ncbi.nlm.nih.gov/pubmed/21731487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002085
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