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The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine

Pharmacokinetics, pharmacodynamics and pharmacogenetics play an important role in drug discovery and contribute to treatment success. This is an essential issue in cancer treatment due to its high toxicity. During the last decade, cyclin-dependent kinase inhibitors were recognised as a new class of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hassan, Moustapha, Sallam, Hatem, Hassan, Zuzana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121020/
https://ncbi.nlm.nih.gov/pubmed/21969887
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