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CD39(+ )Regulatory T cells suppress generation and differentiation of Th17 cells in human malignant pleural effusion via a LAP-dependent mechanism

BACKGROUND: Both regulatory T cells (Tregs) and T helper IL-17-producing cells (Th17 cells) have been found to be involved in human malignancies, however, the possible implication of Tregs in regulating generation and differentiation of Th17 cells in malignant pleural effusion remains to be elucidat...

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Détails bibliographiques
Auteurs principaux: Ye, Zhi-Jian, Zhou, Qiong, Zhang, Jian-Chu, Li, Xiao, Wu, Cong, Qin, Shou-Ming, Xin, Jian-Bao, Shi, Huan-Zhong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120670/
https://ncbi.nlm.nih.gov/pubmed/21663645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-77
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