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Critical role for IL-21 in both primary and memory anti-viral CD8(+) T-cell responses

While it is well established that CD8(+) T cells generated in the absence of CD4(+) T cells mediate defective recall responses, the mechanism by which CD4(+) T cells confer help in the generation of CD8(+) T-cell responses remains poorly understood. To determine whether CD4(+) T-cell-derived IL-21 i...

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Bibliografiset tiedot
Päätekijät: Barker, Brianne R., Gladstone, Michael N., Gillard, Geoffrey O., Panas, Michael W., Letvin, Norman L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119210/
https://ncbi.nlm.nih.gov/pubmed/21061439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939939
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