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Endoplasmic Reticulum Stress and the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

The underlying causes of nonalcoholic fatty liver disease (NAFLD) are unclear, although recent evidence has implicated the endoplasmic reticulum (ER) in both the development of steatosis and progression to nonalcoholic steatohepatitis. Disruption of ER homeostasis, often termed “ER stress,” has been...

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Main Authors: Gentile, Christopher L., Frye, Melinda, Pagliassotti, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118611/
https://ncbi.nlm.nih.gov/pubmed/21128705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3790
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