Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy

BACKGROUND: NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2), containing one iron sulfur cluster ([2Fe-2S] binuclear cluster N1a), is one of the core nuclear-encoded subunits existing in human mitochondrial complex I. Defects in this subunit have been associated with Parkinson's disease,...

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Autores principales: Liu, Hsin-Yu, Liao , Pin-Chao, Chuang, Kai-Tun, Kao, Mou-Chieh
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117770/
https://ncbi.nlm.nih.gov/pubmed/21548921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-29
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