Galectin 3 Induces a Distinctive Pattern of Cytokine and Chemokine Production in Rheumatoid Synovial Fibroblasts via Selective Signaling Pathways

OBJECTIVE: High expression of galectin 3 at sites of joint destruction in rheumatoid arthritis (RA) suggests that galectin 3 plays a role in RA pathogenesis. Previous studies have demonstrated the effects of galectins on immune cells, such as lymphocytes and macrophages. This study was undertaken to...

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Hlavní autoři: Filer, Andrew, Bik, Magdalena, Parsonage, Greg N., Fitton, John, Trebilcock, Emily, Howlett, Katherine, Cook, Michelle, Raza, Karim, Simmons, David L., Thomas, Andrew M. C., Salmon, Mike, Scheel-Toellner, Dagmar, Lord, Janet M., Rabinovich, Gabriel A., Buckley, Christopher D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116228/
https://ncbi.nlm.nih.gov/pubmed/19479862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24574
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