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Syntheses and Pharmacological Evaluations of Novel N-substituted Bicyclo-heptan-2-amines at NMDA Receptors
Several novel norcamphor (bicycloheptane) based compounds were designed and synthesized as noncompetitive NMDA receptor antagonists at the Phencyclidine (PCP) binding sites. The heterocyclic ring was also varied to examine piperidine, pyrrolidine and morpholine groups. We examined pharmacological ac...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115441/ https://ncbi.nlm.nih.gov/pubmed/21496213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2011.01124.x |
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