Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells

Engraftment and maintenance of hematopoietic stem and progenitor cells (HSPC) depend on their ability to respond to extracellular signals from the bone marrow microenvironment, but the critical intracellular pathways integrating these signals remain poorly understood. Furthermore, recent studies pro...

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Detalles Bibliográficos
Autores principales: Sanchez-Aguilera, Abel, Lee, Yun-Jung, Lo Celso, Cristina, Ferraro, Francesca, Brumme, Kristina, Mondal, Subhanjan, Kim, Chaekyun, Dorrance, Adrienne, Luo, Hongbo R., Scadden, David T., Williams, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111279/
https://ncbi.nlm.nih.gov/pubmed/21606370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102018108
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