The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen

INTRODUCTION: The purpose of the present study was to investigate the relationship of expression of hypoxia inducible factor (HIF)-1α-modifying enzymes prolyl hydroxylase (PHD)1, PHD2 and PHD3 to response of tumours and survival in breast cancer patients enrolled in a phase II trial of neoadjuvant a...

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Autors principals: Fox, Stephen B, Generali, Daniele, Berruti, Alfredo, Brizzi, Maria P, Campo, Leticia, Bonardi, Simone, Bersiga, Alessandra, Allevi, Giovanni, Milani, Manuela, Aguggini, Sergio, Mele, Teresa, Dogliotti, Luigi, Bottini, Alberto, Harris, Adrian L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109585/
https://ncbi.nlm.nih.gov/pubmed/21291529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2825
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