l-Histidine-based pH-sensitive anticancer drug carrier micelle: Reconstitution and brief evaluation of its systemic toxicity

Adoxorubicin (DOX)-carrier micellar system consisting of poly(histidine)(5K)-b-poly(ethylene glycol)(2K) and poly(l-lactic acid)(3K)-b-PEG(2K)-folate has been developed targeting the early endosomal pH and it have been convincingly proved that intracellular high dose strategy using such micelles is...

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Bibliographic Details
Main Authors: Oh, Kyung T., Lee, Eun Seong, Kim, Dongin, Bae, You Han
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108151/
https://ncbi.nlm.nih.gov/pubmed/18407443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.03.003
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