Učitavanje...
A requirement of STAT3 DNA-binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors
Both STAT3 and NF-κB are persistently activated in diverse cancers, promoting tumor cell proliferation, survival, angiogenesis and metastasis through transcriptional activation of multiple common genes. Paradoxically, STAT3 also suppresses many NF-κB-inducible genes involved in innate and adaptive a...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107358/ https://ncbi.nlm.nih.gov/pubmed/21502401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3304 |
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