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CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

Copy number variation (CNV) in the genome is a complex phenomenon, and not completely understood. We have developed a method, CNVnator, for CNV discovery and genotyping from read-depth (RD) analysis of personal genome sequencing. Our method is based on combining the established mean-shift approach w...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Abyzov, Alexej, Urban, Alexander E., Snyder, Michael, Gerstein, Mark
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cold Spring Harbor Laboratory Press 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106330/
https://ncbi.nlm.nih.gov/pubmed/21324876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.114876.110
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