Vaccination with Plasmodium knowlesi AMA1 Formulated in the Novel Adjuvant Co-Vaccine HT™ Protects against Blood-Stage Challenge in Rhesus Macaques

Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading blood stage vaccine candidate. Plasmodium knowlesi AMA1 (PkAMA1) was produced and purified using similar methodology as for clinical grade PfAMA1 yielding a pure, conformational intact protein. Combined with the adjuvant CoVaccine...

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Autors principals: Mahdi Abdel Hamid, Muzamil, Remarque, Edmond J., van Duivenvoorde, Leonie M., van der Werff, Nicole, Walraven, Vanessa, Faber, Bart W., Kocken, Clemens H. M., Thomas, Alan W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105089/
https://ncbi.nlm.nih.gov/pubmed/21655233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020547
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