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Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides
One of the most frequent modifications in proteins and peptides is the deamidation of asparagine, a spontaneous non-enzymatic reaction leading to a mixture of ***L,D-succinimidyl, L,D-aspartyl, and L,D-isoaspartyl forms, with L-isoaspartyl dominating. Spontaneous isomerization of L-Asp yields the sa...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104603/ https://ncbi.nlm.nih.gov/pubmed/20446295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201000027 |
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