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Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides

One of the most frequent modifications in proteins and peptides is the deamidation of asparagine, a spontaneous non-enzymatic reaction leading to a mixture of ***L,D-succinimidyl, L,D-aspartyl, and L,D-isoaspartyl forms, with L-isoaspartyl dominating. Spontaneous isomerization of L-Asp yields the sa...

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Bibliografski detalji
Glavni autori: Yang, Hongqian, Zubarev, Roman A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104603/
https://ncbi.nlm.nih.gov/pubmed/20446295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201000027
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