Association Between a Functional Variant Downstream of TNFAIP3 and Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE, OMIM 152700) is an autoimmune disease characterized by self-reactive antibodies resulting in systemic inflammation and organ failure. TNFAIP3, encoding the ubiquitin-modifying enzyme A20, is an established susceptibility locus for SLE. By fine mapping and genomic r...

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Main Authors: Adrianto, Indra, Wen, Feng, Templeton, Amanda, Wiley, Graham, King, Jarrod B., Lessard, Christopher J., Bates, Jared S., Hu, Yanqing, Kelly, Jennifer A., Kaufman, Kenneth M., Guthridge, Joel M., Alarcón-Riquelme, Marta E., Anaya, Juan-Manuel, Bae, Sang-Cheol, Bang, So-Young, Boackle, Susan A., Brown, Elizabeth E., Petri, Michelle A., Gallant, Caroline, Ramsey-Goldman, Rosalind, Reveille, John D., Vila, Luis M., Criswell, Lindsey A., Edberg, Jeffrey C., Freedman, Barry I., Gregersen, Peter K., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kimberly, Robert P., Martin, Javier, Merrill, Joan T., Niewold, Timothy B., Park, So-Yeon, Pons-Estel, Bernardo A., Scofield, R. Hal, Stevens, Anne M., Tsao, Betty P., Vyse, Timothy J., Langefeld, Carl D., Harley, John B., Moser, Kathy L., Webb, Carol F., Humphrey, Mary Beth, Montgomery, Courtney Gray, Gaffney, Patrick M.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103780/
https://ncbi.nlm.nih.gov/pubmed/21336280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.766
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