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A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle

The human developmental diseases Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS) are both caused by mutations in proteins responsible for sister chromatid cohesion. Cohesion is mediated by a multi-subunit complex called cohesin, which is loaded onto chromosomes by NIPBL. Once on chromos...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mönnich, Maren, Kuriger, Zoë, Print, Cristin G., Horsfield, Julia A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102698/
https://ncbi.nlm.nih.gov/pubmed/21637801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020051
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