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Na(+) imaging reveals little difference in action potential–evoked Na(+) influx between axon and soma

In cortical pyramidal neurons, the axon initial segment (AIS) is pivotal in synaptic integration. It has been asserted that this is because there is a high density of Na(+) channels in the AIS. However, we found that action potential–associated Na(+) flux, as measured by high-speed fluorescence Na(+...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fleidervish, Ilya A, Lasser-Ross, Nechama, Gutnick, Michael J, Ross, William N
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102307/
https://ncbi.nlm.nih.gov/pubmed/20543843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2574
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