Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

DNA methylation has a role in mediating epigenetic silencing of CpG island genes in cancer and other diseases. Identification of all gene promoters methylated in cancer cells “the cancer methylome” would greatly advance our understanding of gene regulatory networks in tumorigenesis. We previously de...

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Autors principals: Hoque, Mohammad Obaidul, Kim, Myoung Sook, Ostrow, Kimberly Laskie, Liu, Junwei, Wisman, G. Bea A., Park, Hannah Lui, Poeta, Maria Luana, Jeronimo, Carmen, Henrique, Rui, Lendvai, Ágnes, Schuuring, Ed, Begum, Shahnaz, Rosenbaum, Eli, Ongenaert, Maté, Yamashita, Keishi, Califano, Joseph, Westra, William, van der Zee, Ate G.J., Van Criekinge, Wim, Sidransky, David
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102297/
https://ncbi.nlm.nih.gov/pubmed/18413733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5913
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