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Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin

Bitter taste stimuli are detected by a diverse family of G protein-coupled receptors (GPCRs) expressed in gustatory cells. Each bitter taste receptor (TAS2R) responds to an array of compounds, many of which are toxic and can be found in nature. For example, human TAS2R16 (hTAS2R16) responds to β-glu...

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Autors principals: Greene, Tiffani A., Alarcon, Suzanne, Thomas, Anu, Berdougo, Eli, Doranz, Benjamin J., Breslin, Paul A. S., Rucker, Joseph B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101243/
https://ncbi.nlm.nih.gov/pubmed/21629661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020123
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