Antiproliferative Effects of Cucurbitacin B in Breast Cancer Cells: Down-Regulation of the c-Myc/hTERT/Telomerase Pathway and Obstruction of the Cell Cycle

Naturally occurring cucurbitacins have been shown to have anticancer, antimicrobial and anti-inflammatory activities. In this study, we determined the effects of cucurbitacin B extracted from the Thai herb Trichosanthes cucumerina L. on telomerase regulation in three human breast cancer cell lines (...

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Main Authors: Duangmano, Suwit, Dakeng, Sumana, Jiratchariyakul, Weena, Suksamrarn, Apichart, Smith, Duncan R., Patmasiriwat, Pimpicha
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100835/
https://ncbi.nlm.nih.gov/pubmed/21614210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11125323
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