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Transgenic Over-Expression of Growth Differentiation Factor 11 Propeptide in Skeleton Results in Transformation of the Seventh Cervical Vertebra Into a Thoracic Vertebra

Growth differentiation factor 11 (GDF11) is one of the significant genes that control skeletal formation. Knockout of GDF11 function causes abnormal patterning of the anterior/posterior axial skeleton. The mRNA of GDF11 is initially translated to a precursor protein that undergoes a proteolytic clea...

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Autors principals: LI, ZICONG, KAWASUMI, MIYURI, ZHAO, BAOPING, MOISYADI, STEFAN, YANG, JINZENG
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099245/
https://ncbi.nlm.nih.gov/pubmed/21049546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.21252
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