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Sandwich-Cultured Hepatocytes: An In Vitro Model to Evaluate Hepatobiliary Transporter-Based Drug Interactions and Hepatotoxicity

Sandwich-cultured hepatocytes (SCH) are a powerful in vitro tool that can be utilized to study hepatobiliary drug transport, species differences in drug transport, transport protein regulation, drug-drug interactions, and hepatotoxicity. This review provides an up-to-date summary of the SCH model, i...

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書誌詳細
主要な著者: Swift, Brandon, Pfeifer, Nathan D., Brouwer, Kim L.R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097390/
https://ncbi.nlm.nih.gov/pubmed/20109035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903491881
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