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Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling

Pancreatic ductal adenocarcinoma (PDAC) is characterised by a strong desmoplastic reaction where the stromal compartment often accounts for more than half of the tumor volume. Pancreatic stellate cells (PSC) are a central mediator of desmoplasia. There is increasing evidence that the desmoplasia is...

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Bibliografiske detaljer
Main Authors: Mantoni, Tine S., Lunardi, Serena, Al-Assar, Osama, Masamune, Atsushi, Brunner, Thomas B.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097171/
https://ncbi.nlm.nih.gov/pubmed/21558392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1633
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