Paradoxical relationship between chromosomal instability and survival outcome in cancer

Chromosomal instability (CIN) is associated with poor prognosis in human cancer. However, in certain animal tumour models elevated CIN negatively impacts upon organism fitness, and is poorly tolerated by cancer cells. To better understand this seemingly contradictory relationship between CIN and can...

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Detaylı Bibliyografya
Asıl Yazarlar: Birkbak, Nicolai J., Eklund, Aron C., Li, Qiyuan, McClelland, Sarah E., Endesfelder, David, Tan, Patrick, Tan, Iain B, Richardson, Andrea L., Szallasi, Zoltan, Swanton, Charles
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096721/
https://ncbi.nlm.nih.gov/pubmed/21270108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3667
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