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A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides

Over the last decade a significant number of studies have highlighted the central role of host antimicrobial (or defence) peptides in modulating the response of innate immune cells to pathogen-associated ligands. In humans, the most widely studied antimicrobial peptide is LL-37, a 37-residue peptide...

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Main Authors: Robinson, Mark W., Donnelly, Sheila, Hutchinson, Andrew T., To, Joyce, Taylor, Nicole L., Norton, Raymond S., Perugini, Matthew A., Dalton, John P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093369/
https://ncbi.nlm.nih.gov/pubmed/21589904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002042
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