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Synthesis and sensing of bisphosphonophosphate alkyl monoesters: A novel class of compounds for the study of nucleoside 5′-triphosphate chemistry

A series of novel β,γ-methylene-, monofluoromethylene-, and difluoromethylene-bisphosphonophosphate alkyl monoesters was synthesized. The compounds were conveniently detected during preparative HPLC using post-column derivatization with a phosphate-specific chemosensor.

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Detalhes bibliográficos
Principais autores: Chamberlain, Brian T., Osuna, Jorge, Kashemirov, Boris A., McKenna, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091817/
https://ncbi.nlm.nih.gov/pubmed/21572560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10426507.2010.526675
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